The Portugal captain took his total in the competition to 103 with the three goals, making Real the favourites to qualify for the final.
Sergio Ramos confirmed afterwards, that authorities had held the 32-year-old back for a routine random drugs test.
“He had to undergo a doping test, so we couldn’t see him,” the club captain announced to the media.
“Obviously when Cristiano is in good form, Real Madrid make the most out of it.
“I want to congratulate him because he is unique.
“When he is playing well, Real Madrid are a different team.”